The sperm donor with a rare cancer mutation is associated with 10 cases of cancer in children

It is reported that sperm from one donor in Europe Think at least 67 pregnancyAlthough the donor had a rare mutation that causes cancer.

The donor mutation was related to the diagnosis of 10 children, the Guardian said.

The case was handed down after two families separately contacted their utility clinics after their Diagnosis of baby cancer were associated with a rare genetic option called TP53.

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Mutation in Gene TP53 causes li-fraumeni syndrome, which increases the risk of all develops cancer. The Cleveland Clinic claims that this disorder comes with 90% likely to develop some cancer type under 60 years, and 50% to 40 years.

The European Sperm Bank, the sperm supplier, confirmed that this option was present in some donor sperm.

Researcher Dr. Edwidge Casper (not in the picture) stands for the European limit for the number of childbirth and families for one donor. (Istock)

The Guardian reported that the rare version was “not known that he had been linked to cancer during the 2008 donation.”

The genetic version is reported to have not been detected with a standard survey, and the donor is said to be in good health.

“The detected mutation is the one that could not be detected by screening methods that we use according to the rules.”

D -R Edwidge Casper, Biologist of the University Hospital Ren in France, last week presented this case at the annual European Human Genetics Conference in Milan, commenting on the need for the European limit on The number of births Either families for one donor.

“We cannot make a sequence of a whole genom for all sperm donors-I don’t argue for it,” she said The Guardian. “But this is an abnormal spread of genetic disease. Not every person across Europe is 75 children.”

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Casper analyzed the mutation in his laboratory, concluded that it was most likely to cause cancer and that children born from this donor should “receive genetic counseling.”

The research traced 67 children from 46 families in eight European countries. A Children have passed the checkwith an option found in 23 of them.

It was reported that the 10 cancer was diagnosed with the cases of leukemia and lamphous lymphoma.

Sixty -seven children from 46 families were discovered from a donor to eight European countries. (Istock)

In a statement aimed at Fox News Digital, the European Sperm Bank stated that the donor reproduction “usually remains a much safe alternative” than a reproduction without Genetic screening.

The bank added that sperm donors undergo a “comprehensive health examination”, which includes in -depth medical examination, review of the history of the donor family disease and “wide” testing on genetic and Infectious diseases.

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“However, it is impossible to exclude all the risks – and, in this particular case, the detected mutation is the one that could not be identified by the check methods that we use in accordance with the rules and require specialized genetic testing,” the group said.

Julie Pauli Budz, Vice President. Corporate Communications at the European Sperm Bank, expressed by the digital Fox News that they are “deeply affected by this case”.

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“The donor was carefully tested even outside the necessary standards, but preventive genetic screening reaches its borders here,” she said.

“Everyone has about 20,000 genes, and it is simply impossible to detect mutations that cause a person’s disease when you don’t know what you are looking for.”

Eggs and semen are stored in the liquid nitrogen side in the Berlin fertility center. (Jens Kalane/Alliance Picture Alliance through Getty Images)

The Budz noted that the European Sperm Bank welcomes the “continuation of the dialog” regarding the establishment of “International Compulsory Family Limit”, which they have advocated “several times, also at the EU level”.

“That’s why, except for the performance of national Restrictions of pregnancyWe actively implemented our own international limit in 75 families per donor, ”she added.

What to know about the governing principles of US sperm donation

There is no official legal restriction in the US in how many semen donations can make one person.

However, the American Society of Reproductive Medicine (ASRM) recommends that donors limit 25 live births within each area of ​​800,000 people.

“Institutions, clinics and sperm banks must keep sufficient records to allow a restriction for The amount of pregnancy What the donor is responsible for, “ASRM said on its site.

“Restriction of danar vials is an important part of the process.”

The California Cryobank, who claims to have the highest choice of semen and egg donations in the country, states on its site that it closely monitors donors to limit the total number of family units to 20-30 worldwide.

“Restriction of danar vials is an important part of the process,” the bank said.

The US Federal Office requires that all sperm donors undergo a physical examination, fill out a questionnaire, submit a medical history and check for infectious diseases in the laboratory approved by FDA. (Istock)

The US Federal Directorate (FDA) requires that all sperm donors undergo a physical examination, fill out a questionnaire, submit a medical history and check for infectious diseases in the laboratory approved by the FDA.

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“Legal consultations and laws may vary depending on the state,” the organization notes.

In California Cryobank donors should be checked for infectious diseases, undergo genetic screening, get a psychological assessment and verification of criminal verification, as well as checking the verification Zika virusIt is reported on the bank’s website.