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Chikowore says there are many possible explanations for it, who vary from how you still didn’t make a variant yet yet to the ficiological structure of the pancreas. The last theory arises from Search performed in Eastern Africthat found some men develop type 2 diabetes despite having a healthy weight. Do not Continuous study LED by medical search advice, in partnership with UK searchers, measure the size of pancreas in such men and evaluate their function.
“These cases seems to be bolded to fat, so we want to try and understand what is going on”, says Chikowore. “It’s genetic? Or the cause of the pancreas has developed to malnutrition in the nala, impacting the development of cells beat so he doesn’t produce aside.”
And well reassess the path to the new treatments, understanding these cases could lead to tools for the mergey skim. Actually the golden methods and that gloomy-sugar vacuarial, and missing blood sugar, and missing hba1c which i know hba1c of blood sugar for the water for the time of fire. But such tests are being shown to be ineffective in some populations.
Last year a major study Elliligated that a significant number of people of the African artice are squarely fadals two could be, because they bring reference in a enzym called G6PD. This genetic variation is relatively common In parts of sub-saharan africa because of the protection against levels, but also reduced to the sort of the study of the study of the sight of complications scheduled as the diabetic, which may cause the blindness.
Meanwhile, circling like julia gasteeck, a professor and barefoot malchand on the seducent medical women on the woman listen to the patient of significant fat. “The flucing of the fasting is often used as a mark of risk diabetes, but this is because the fat of the glucose level fat.” Says goedecke. “In African is actually a poor marker, because most of the diabetes have low fat, so often miss diabetes if only a raping value of the waste.”
Instead of fat The search of goedecke He indicated that many of these cases are being raised by an engaged ability to shrink of blood, that cause notice of insulous levels.
GadeEck and others are now indicating a study women from the South Guard, different communities in Ghana, the Dutch and the Netherlands and Netherlands. They regularly evaluate a range of biological features on a number of years. “We hope this data also will give you a better understanding of immixed mechanoms, and ideas for interventions to try it in:” she says.
While searching in diabetes through Africa have direct impacts for the patients in the region, chikowore believes that might be all benefit with the disease. The understanding because of the girls of sub-saharan’s african fare to earn the liver fat, for example, could lead to the development of the drug that may improve metabolic health in other metabolic groups. “With diversity, you have both extremes of the spectrum: Populces that are susceptible and people who protected,” says. “And we’ve got bigger chance to find these people in Africa that else.”
As an example of what may be possible, chianched gené geese guided to the new class of Calester, with a company “imagines if we could be one day for the diabetes,” says. “A genetically informed drug that can make people diabetes-proof. I think that’s what the world is looking.”
