As the bond of two brain molecules creates memories that last a life

The original version of this story appeared in How much magazine. I am

By the time Undd sacktor was to turn 3, their sister of 4 years old bite of leukemia. “A empty fall next to mine. A set of swing with two seats instead of one:” He said, you remembered, tracks at the end of his or her printer. “There was this person missed – so I had a single memory.” That memory, DEEINT, but forget, was installed in the beautiful gods of his house. A young sculptur asked her sister to read a book and she burns out: “I’m going to ask your mother”. Sachtor Glumly finds the stairs to the kitchen.

It is recharge that, over 60 years later, the sachtor remembers this childhood in all. The wonderful nature of the memory is that every reminder is a physical trail, impact in brain tissue from neuron molcher. As the essence of a living moment is coded and then retrieved remains one of the unresponsive questions in neuroscency.

The bag has become neuroscantist in search of a response. At the University of New Yorkly in Brooklyn, stretches the mollius involved in neural connections. The question you have always held his attention was first articulated in 1984 From the Fame of Francis Cryculas: How do you remember years, even decreased, when the decreging body molecules and are replaced in a mattress, weeks or less years?

In 2024, working next to a team that includes their longime glue André Fentona neurosierist at New York University, a bag has offered a potential explanation in a published paper in Advance of science. I am The researchers discovered that a persistent bond between two proteins It is associated with the synaming reinforcement, which are the connections between neurons. Synthetic sync is designed to be fundamental to memory training. As some degrade protein, new take their place in a moleculary molecular swap that maintains the integration and, so, the memory.

In 1984, Francis Crick described a biological convention: Memories in more years, how much to more mamous degrade or weeks. “How is the memory looked in the brain for his track is relatively immune to the molecular fact?” Write in the wild.

Photograph: National Library of Medicine / Science

Present researchers “a very convincing case” that “interaction between these two molecules is required for memory storage”, he said Karl Peter GIESEa neurobiologist in the King’s college that was not involved with work. Results offer a convincing response to cricking dilemma, grabbing discouragements to explain how ephimic molecules keeps the memories that last a life.

Molecular memory

First in his career, a bag made a discovery that will train the rest of their life. After studying under the memory of James Schwartz at Mibia, opened his lab to look for a molecules that might help explain.

The molecule was looking serious in brain summary. In 1949, the Donald Hebb Psychologist that sticky sticky if you force the connections between the legs, or, as well as they are together. “In the decades since, many studies suggested that the strongest connection between neurons that have memories, the best memories persist.

In the beginning of the 1990s, in a lobe in his lab, constructed a slice of a brain brain had the black path then he sought any molecular change that had occurred. Whenever you repeat the experiment, he saw high levels, a certain protein in dry. “At the Storm Tomea, I was so, here,” he said.