Crispula offers new hope to handle diabetes

Eclipology Technology of Cripe showed their revolutionary potential in the last few years: it has been used treat rare diseasesat Adapt crops to resist the extremities of climate change, or even to Change the color of a spider web. But the greatest hope is that this technology will help find a care for global disease, as Diabetes. I am A new study point in that direction.

For the first time, researchers have succeeded in a man with the diabetes of Type 1, autoimmune disease the immune systems of insulin production in the pancreas. Unsuspin, the body is then unable to regulate blood sugar. If the steps are not taken to handle glucose levels (typically, insulin), this may lead to the nerves and organs – especially the heart, revoles and eyes. Almost a little 9.5 million world people have type 1 diabetes.

In this experiment, the Edited cells produce insulins per months after being implanted, no consignee to take any immunosuppressive drugs to stop the body. The crisis technology allowed the researchers to dot the cells genetically modify with camouflage to evade detection.

The study, published last month in The new journal of medicine, details the procedure of the step. First, the charmed islands were taken by a donor without diabetes, and the dwells of evades. The clls has hidden the ication of the schrepfer of the Califernia, the company that has developed this treat.

The edited cells were implant in the patient’s forearm muscle, and after 12 weeks, no refusal signs has been detected. (A Subsequent report By the baliades notes of that the impantate cells were always for the immune immune of the Patient after six months.)

Tests run as part of the registered study that blinds have been functional: Unsolicoles insuline in response, which represented a control step without insulity need. Four adverse events have been recorded during the furrow, but none were serious or directly related to modified cells.

The ultimate goal of researchers are to apply cell geneickers – who have the ability to reproduce themselves in other cells of the body and after insulin. “The advantage of the haze’s cells is that when these striped cells and create new cells, new things are also the” schrepfer explained in a Chedri-Sinai Q + a before this year.

Traditionally transplanting foreign cells in a patient needs suppressing the patient’s immune system to avoid being rejected. This brings significant risks: Infection, toxicity, and long-term complications. “Seeing the patients die from refuses to be frustrated by my career about the immunee’s refuge,” Schrepfer has told CEDARS-Sinai.

Although the research marked in the search of treatments 1 study type of the study type, which he received a low cells for a bloodless of injected insulin. A editorial from the newspaper Nature It says some independent research failed in their efforts to confirm that healthy method provides edited cells with the ability to evade the immune system.

Sana will be looking for more clinical trials beginning next year. Without transmission and restraint of the current study, the possibility of the transplant’s chance they modified to be invisible to the immune system that is very prominent dating.

This story has originally Wired in Spanish and has been translated by Spanish.